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Bioidentical Hormones: Understanding Your Options in Perimenopause & Menopause

If you’re experiencing changes in sleep, mood, energy, hot flushes, or discomfort during sex, you’re certainly not alone. These changes are common during perimenopause and menopause, and there are several evidence-based options that may support you through this transition.


I’m Jenna, your Nurse Practitioner and menopause educator. This guide helps make sense of the different hormone therapy options available in Australia, how they work, and how to approach treatment in a way that’s safe, informed and tailored to you.


What does “bioidentical” actually mean?

Bioidentical hormones have the same molecular structure as the hormones your ovaries produced before menopause. These include:

  • Oestradiol (the main form of oestrogen)

  • Micronised progesterone

  • Physiologic-dose testosterone (for specific indications)

In Australia, bioidentical hormones are available in two forms:


TGA-approved bioidentical products

These are standardised, regulated medicines (patches, gels, capsules, tablets).


Compounded bioidentical hormones*

These may be considered when:

  • a person cannot tolerate TGA-approved products

  • they require an excipient-free option

  • a specific dose or formulation is needed that is not commercially available

Because compounded products are not TGA-approved and may vary in strength and purity, they are not first-line in Australian and international guidelines.

However, they can be appropriate in selected cases following an individualised discussion of risks, benefits and alternatives.

This means compounded options remain available — just not the default starting point.

*Always discuss risks like inconsistent dosing/purity with your practitioner


Bioidentical, Synthetic and Compounded Hormones – Understanding the Differences

Both synthetic and bioidentical hormones have been used safely for decades and are supported by substantial international research. The best choice depends on symptoms, health history, preferences and individual tolerability.

Below is a simple, AHPRA-compliant comparison of key characteristics, not expected outcomes.


Key Characteristics of Hormone Therapy Options

(AMS, NAMS, NICE, Monash Toolkit — 2024–2025)Individual suitability varies; outcomes are not guaranteed.



Treatment Options in Australia

Depending on your symptoms and where you are in the menopause transition, options may include:

  • Oestradiol (gel, patch or tablet)

  • Micronised progesterone

  • Combined oestrogen–progestin tablets

  • Low-dose vaginal oestrogen for dryness and discomfort

  • Testosterone for low sexual desire when clinically indicated

Suitability varies from person to person. Age, medical history, personal risk factors and prior responses to treatment all help guide decision-making.


A simple way to explore your options

Here’s a supportive way to begin:

  1. Track your symptoms for 2–4 weeks.

  2. Book a longer consultation to allow time for discussion.

  3. Bring this newsletter and ask:


    “Which option aligns best with my health history and goals?”

Hormone therapy often requires minor adjustments over time to find the right fit.


Non-hormonal choices

Some women prefer non-hormonal options or cannot use hormones. Evidence-based alternatives include:

  • Non-hormonal medications for hot flushes

  • Cognitive behavioural strategies for flushes and sleep

  • Regular vaginal moisturisers and lubricants

  • Strength training, movement and sleep optimisation

  • Tracking and reducing personal triggers such as alcohol or caffeine


You’re supported

Perimenopause and menopause are significant life phases. With personalised care, many women find approaches that help improve comfort, confidence and daily wellbeing.


If you’d like support or a personalised plan, you can reach me at:


Warmly,

Jenna

Nurse Practitioner & Menopause Educator


Sources (2024–2025)

Australasian Menopause Society (AMS)NICE NG23North American Menopause Society (NAMS)Monash University Practitioner ToolkitJean Hailes for Women’s HealthTherapeutic Goods Administration (TGA)


Medical Disclaimer

This newsletter contains general information only and does not replace personalised medical advice. Hormone therapy is not suitable for everyone. All treatment decisions should be made in consultation with a qualified health professional.

 
 
 

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